Articles co-published by
Senexis:
O’Hare, E., Scopes, D.I, Treherne, J.M.,
Norwood, K., Spanswick, D., and Kim, E.M. (2010). RS-0406
Arrests Amyloid-beta Oligomer-Induced Behavioural Deterioration In Vivo.
Behav.
Brain Res. In Press.
To
read the abstract click here
Amijee, H. and Scopes, D. (2009).
The Quest for Small Molecules as
Amyloid Inhibiting Therapies for Alzheimer’s Disease.
Journal of Alzheimer’s Disease,
Volume 17, Number 1,
33-47 To see review click here
but do not download or print
Amijee, H., Nerou, E., Scopes, D., Treherne, J.M.,
O’Hare, E.,
Jeggo, R., Whyment, A. and Spanswick, D. (2008).
SEN1269: A Novel Inhibitor of Amyloid Beta Toxicity.
Alzheimer’s Association International Conference
on Alzheimer’s Disease.
Chicago, U.S.A.
To download the
poster click here
Amijee, H., Doig, A.J., Nerou, E., Scopes, D.I.C.
and Treherne. J.M. (2008). β-Amyloid Aggregation
Inhibitors for the Treatment of Alzheimer's Disease.
Alzheimer’s Association International Conference
on Alzheimer’s Disease.
Chicago, U.S.A.
To download the
poster click here
Kim, E-M., Gannon, J., Norwood, K., Scopes, D.,
Treherne, J.M. and
O’Hare, E. (2008). SEN1269 Arrests
Behavioural Deterioration Induced Following ICV
7PA2 Injections in the Rat. 18th Alzheimer
Europe Conference.
Oslo, Norway.
To download the
poster click here
Treherne, J.M.
and Scopes, D.I.C. (2008) "Is amyloid-related toxicity
an inevitable consequence of ageing?" Drug Discovery World
(Spring 2008), 21-24.
To read
this article click here
Kokkoni,
N., Stott, K., Amijee, H., Scopes, D.I.C., Treherne, J.M. and Doig, A.J.
(2007) "Rationally Designed Inhibitors of Amyloid Toxicity". Biochemical Society Transactions,
Volume 35(3), P009.
To purchase the article click here
Kokkoni, N., Stott, K., Amijee, H.,
Mason, J.M. and Doig, A.J. (2006). "N-Methylated peptide inhibitors of
beta-amyloid aggregation and toxicity". Optimization of the inhibitor
structure". Biochemistry 45 (32), 9906-18.
Treherne, J.M. (2006). "When old money meets new science".
BioPartnering Today Winter issue 2005/2006, 12-15.
To purchase the article click here
Amijee, H. Kokkoni, N., Doig, A.J., Stott, K.R., Treherne, J.M.
& Scopes, D.I.C (2005). “Meptides: N-Methylated Peptides -
Comparison with other peptides and small molecule Aβ
aggregation inhibitors”. Biochemical Society Transactions,
Volume 33(4), P091.
To purchase the article click here
Amijee, H. Kokkoni, N., Doig, A.J.,
Stott, K.R., Treherne, J.M. & Scopes, D.I.C (2005). “Meptides: N-Methylated
Peptides - Comparison with other peptides and small molecule Aβ
aggregation inhibitors”. BioScience 2005: from genes to systems,
Published July, P0594, Biochemical Society, Glasgow
To purchase the article click here
Collins, D.R., Amijee, H. & Treherne,
J.M. (2004). "Reversal of
β-amyloid
induced depression of long-term potentiation by inhibitors of protein
folding in rat hippocampal slices". Soc. Neurosci. Abstr. 29.
To find the article click here
Doig, A.J., Stott, K. and Treherne, J.M. (2004).
"Inhibitors of Amyloid
Aggregation: Technologies for the Discovery of Novel Lead Compounds".
Biotechnology and Genetic Engineering Reviews
21,
197-211.
To purchase this article from the British Library click here
Stott, K. and Doig, A. J. (2003). "Meptides: a novel class of synthetic peptide derivatives for the potential
treatment of Neurodegenerative diseases".
European BioPharmaceutical Review
Spring Issue 2003.
To
read the abstract click here
Mason, J.M., Kokkoni, N., Stott, K. and Doig, A.J. (2003).
"Design Strategies
for anti-amyloid agents". Current Opinions in Structural Biology
13(4), 526-532.
Stott, K. and Doig, A. J. (2003). "Meptides: a potential treatment for neurodegenerative diseases". Pharmaceutical Visions, Spring 2003, 4-8.
Links to articles published by our
scientific advisors:
Prof. Walsh
Prof. Doig
Dr Levine
Prof. Rothwell
