Senexis
Unfolding the Science of Senescence to revolutionise the diagnosis & treatment of ageing-related diseases

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Selected publications on amyloid and related subjects

Articles published by Senexis:

 

Amijee, H., Nerou, E., Scopes, D., Treherne, J.M., O’Hare, E., Jeggo, R., Whyment, A. and Spanswick, D. (2008). SEN1269: A Novel Inhibitor of Amyloid Toxicity. Alzheimer’s Association International Conference on Alzheimer’s Disease. Chicago, U.S.A.

Kim, E-M., Gannon, J., Norwood, K., Scopes, D., Treherne, J.M. and O’Hare, E. (2008). SEN1269 Arrests Behavioural Deterioration  Induced Following ICV 7PA2 Injections in the Rat. 18th Alzheimer Europe Conference. Oslo, Norway. To download the poster click here

 

Treherne, J.M. and Scopes, D.I.C. (2008) "Is amyloid-related toxicity an inevitable consequence of ageing?" Drug Discovery World (Spring 2008), 21-24. To read this article click here

 

Kokkoni, N., Stott, K., Amijee, H., Scopes, D.I.C., Treherne, J.M. and Doig, A.J. (2007) "Rationally Designed Inhibitors of Amyloid Toxicity". Biochemical Society Transactions, Volume 35(3), P009. To read the article click here
 

Kokkoni, N., Stott, K., Amijee, H., Mason, J.M. and Doig, A.J. (2006). "N-Methylated peptide inhibitors of beta-amyloid aggregation and toxicity". Optimization of the inhibitor structure". Biochemistry 45 (32), 9906-18.

Treherne, J.M. (2006). "When old money meets new science". BioPartnering Today Winter issue 2005/2006, 12-15. To purchase the article click here

Amijee, H. Kokkoni, N.,  Doig, A.J., Stott, K.R., Treherne, J.M. & Scopes, D.I.C (2005). “Meptides: N-Methylated Peptides - Comparison with other peptides and small molecule Aβ aggregation inhibitors”. Biochemical Society Transactions, Volume 33(4), P091. To read the article click here

Amijee, H. Kokkoni, N.,  Doig, A.J., Stott, K.R., Treherne, J.M. & Scopes, D.I.C (2005). “Meptides: N-Methylated Peptides - Comparison with other peptides and small molecule Aβ aggregation inhibitors”. BioScience 2005: from genes to systems, Published July, P0594, Biochemical Society, Glasgow To read the article click here

Collins, D.R., Amijee, H. & Treherne, J.M. (2004). "Reversal of β-amyloid induced depression of  long-term potentiation by inhibitors of protein folding in rat hippocampal slices". Soc. Neurosci. Abstr. 29. To search for the article click here

Doig, A.J., Stott, K. and Treherne, J.M. (2004). "Inhibitors of Amyloid Aggregation: Technologies for the Discovery of Novel Lead Compounds". Biotechnology and Genetic Engineering Reviews 21, 197-211. To purchase this article from the British Library click here

Stott, K. and Doig, A. J. (2003). "Meptides: a novel class of synthetic peptide derivatives for the potential treatment of Neurodegenerative diseases". European BioPharmaceutical Review Spring Issue 2003.  To read the abstract click here

Mason, J.M., Kokkoni, N., Stott, K. and Doig, A.J. (2003). "Design Strategies for anti-amyloid agents". Current Opinions in Structural Biology 13(4), 526-532.

Stott, K. and Doig, A. J. (2003). "Meptides: a potential treatment for neurodegenerative diseases". Pharmaceutical Visions, Spring 2003, 4-8.

Links to articles published by our scientific advisors:

Prof. Walsh             Prof. Doig             Dr Levine              Prof. Rothwell